久久久www成人免费毛片麻豆,成人免费在线观看毛片,9久久免费国产精品特黄国产蜜桃,国产精品日韩欧美一区二区视频,亚州av无码乱码精品国产,欧美日韩视频综合一区无弹窗,天堂中文字幕av成人网站

熱門搜索:A549    293T 金黃色葡萄球菌 大腸桿菌 AKK菌
購物車 1 種商品 - 共0元
當前位置: 首頁 > 行業(yè)資訊 > HL-60細胞與NB4細胞的區(qū)別

HL-60細胞與NB4細胞的區(qū)別

HL60細胞株是來自FAB分型中M2型(急性粒細胞白血病部分分化型)患者,而不是M3型(急性早幼粒細胞白血病)患者。這一結(jié)論的得出來自對該患者骨髓細胞的光學和超微結(jié)構(gòu)的形態(tài)學分析。該患者骨髓涂片的分析顯示原始粒細胞占37%,早幼粒細胞占44%,中幼粒細胞以及更成熟階段細胞占8%。HL60細胞株缺少急性早幼粒細胞白血病的一些區(qū)分特征:過氧化物酶染色強度沒有通常的FAB-M3型細胞強;沒有裂片形式的顆?;駻uer小體;內(nèi)質(zhì)網(wǎng)不是非常擴大的。細胞遺傳學檢測顯示在HL60細胞株中沒有發(fā)現(xiàn)15號或17號染色體結(jié)構(gòu)的異常。HL60細胞株所代表的白血病類型是急性粒細胞白血病部分分化型而并非急性早幼粒細胞白血病

相關(guān)文獻:HL-60 cell line was derived from a patient with FAB-M2 and not FAB-M3. Blood. 1988 Jan;71(1):242-7

abstract:The leukemia from which the human cell line HL-60 was derived was classified in 1976 as acute progranulocytic leukemia (APL), although it was recognized to show a number of atypical features. In the ensuing 10 years, the concept of APL and its integral association with t(15;17) has evolved, and the concept of APL as a morphologically recognizable entity has become embodied in the term French-American-British classification M3 (FAB-M3). It is now recognized that not every case of leukemia with a high proportion of progranulocytes can be classified as FAB-M3. We reviewed the light and ultrastructural morphology of the original diagnostic material from this case, and we report that the leukemia from which HL-60 was derived does not conform to the currently recognized entity of FAB-M3 and is more appropriately classified as an acute myeloblastic leukemia with maturation, FAB-M2.

 
德清县| 兴安县| 宝兴县| 汉川市| 海原县| 吉木萨尔县| 江源县| 林芝县| 门头沟区| 微山县| 台北市| 洛扎县| 万山特区| 桑日县| 新龙县| 化州市| 新建县| 河北区| 东乡县| 文安县| 宁波市| 西宁市| 岢岚县| 九江市| 麻江县| 布尔津县| 牡丹江市| 昌乐县| 安丘市| 元氏县| 容城县| 怀来县| 渝中区| 普安县| 汝南县| 乌拉特后旗| 毕节市| 离岛区| 永善县| 大港区| 营山县|