Mesenchymal Stem Cell Chondrogenic Differentiation Supplement (MCDS) is a medium supplement designed for differentiation of primary mesenchymal stem cells (MSCs) to an chondrogenic lineage as determined by Safranin-O staining in vitro. It is a sterile, concentrated (100X) solution. The supplement is designed as an additive for mesenchymal stem cell chondrogenic differentiation medium (MCDM, Cat. No. 7551) and should be used in conjunction with that medium.